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>   home   >   Products   >   Primary Antibodies   >   EIF4EBP3 Antibody   

EIF4EBP3 Antibody

Purified Mouse Monoclonal Antibody (Mab)

  • WB - EIF4EBP3 Antibody AP52866
    Western blot detection of EIF4EBP3 in CHO-K1 cell lysate(B)and CHO-K1 transfected by EGFP-EIF4EBP3 fragment(A)cell lysate using EIF4EBP3 mouse mAb (1:1000 diluted).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60516
Reactivity Transfected
Host Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 11 KDa
Additional Information
Gene ID 8637
Other Names 4E BP3; 4E-BP3; 4EBP3; eIF4E binding protein 3; Eukaryotic initiation factor 4E binding protein 3; Eukaryotic translation initiation factor 4E binding protein 3; OTTHUMP00000159879.
Dilution WB~~1:1000
Format Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Function Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.
Tissue Location Expression is highest in skeletal muscle, heart, kidney, and pancreas, whereas there is very little expression in brain and thymus.
Citations (0)

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Regulates eIF4E activity by preventing its assembly into the eIF4F complex.


Poulin F.,et al.J. Biol. Chem. 273:14002-14007(1998).

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$ 295.00
Cat# AP52866
(40 western blots)
Availability: 5-7 days
Bulk Size
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