|Application ||WB, E|
|Calculated MW||43520 Da|
|Antigen Region||362-391 aa|
|Other Names||Transmembrane protein 79, Mattrin, TMEM79, MATT|
|Target/Specificity||This TMM79 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 362-391 amino acids from the C-terminal region of human TMM79.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TMM79 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Contributes to the epidermal integrity and skin barrier function. Plays a role in the lamellar granule (LG) secretory system and in the stratum corneum (SC) epithelial cell formation (By similarity).|
|Cellular Location||Lysosome. Golgi apparatus, trans-Golgi network. Membrane; Multi- pass membrane protein. Note=Colocalized with TGOLN2 in the trans-Golgi network. Colocalized with LAMP1 in the lysosome (By similarity).|
|Tissue Location||Expressed in the epidermis of the skin. Expressed in epithelial cells of the outermost layer of the stratum granulosum (SG) and hair follicles (at protein level)|
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Provided below are standard protocols that you may find useful for product applications.
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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