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UBAC2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8NBM4 |
| Other Accession | Q8R1K1, Q4R910, Q5ZJQ8 |
| Reactivity | Human, Mouse |
| Predicted | Chicken, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 38964 Da |
| Antigen Region | 63-91 aa |
| Gene ID | 337867 |
|---|---|
| Other Names | Ubiquitin-associated domain-containing protein 2, UBA domain-containing protein 2, Phosphoglycerate dehydrogenase-like protein 1, UBAC2, PHGDHL1 |
| Target/Specificity | This UBAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the N-terminal region of human UBAC2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UBAC2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UBAC2 |
|---|---|
| Synonyms | PHGDHL1 |
| Function | Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets (PubMed:23297223). In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin- mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 (PubMed:31073040). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Dunham, A., et al. Nature 428(6982):522-528(2004)
Christian, S.L., et al. Genomics 79(5):635-656(2002)
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$ 365.00
$ 140.00
Cat# AP5292a
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