UNC50 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| FC, WB, E |
---|---|
Primary Accession | Q53HI1 |
Other Accession | O55227, Q9CQ61, Q7ZUU1, Q3ZBG6 |
Reactivity | Human |
Predicted | Bovine, Zebrafish, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 30373 Da |
Antigen Region | 5-33 aa |
Gene ID | 25972 |
---|---|
Other Names | Protein unc-50 homolog, Periodontal ligament-specific protein 22, PDLs22, Protein GMH1 homolog, hGMH1, Uncoordinated-like protein, UNC50, UNCL |
Target/Specificity | This UNC50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-33 amino acids from the N-terminal region of human UNC50. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | UNC50 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | UNC50 |
---|---|
Synonyms | UNCL |
Function | Involved in the cell surface expression of neuronal nicotinic receptors (By similarity). Binds RNA (By similarity). |
Cellular Location | Nucleus inner membrane {ECO:0000250|UniProtKB:O55227}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O55227}. Golgi apparatus membrane; Multi-pass membrane protein |
Tissue Location | Present in periodontal ligament fibroblasts (at protein level). |
Provided below are standard protocols that you may find useful for product applications.
Background
UNC50 may be involved in cell surface expression of neuronal nicotinic receptors. Binds RNA.
References
Kim, H.J., et al. Cell Tissue Res. 327(1):25-31(2007)
Fitzgerald, J., et al. Brain Res. 877(1):110-123(2000)
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