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AKNA Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
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| AP5317a | DISCONTINED INQUIRE CLICK INQUIRE Add to cart | |||
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
AKNA Antibody (N-term) - Product info | |
| Application | WB, IHC, FC
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| Primary Accession | Q7Z591 |
| Other Accession | NP_110394.3 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 155139 Da |
AKNA Antibody (N-term) - Additional info | |
| Gene ID 80709 | |
| Other Names AKNA; KIAA1968; AT-hook-containing transcription factor | |
| Target/Specificity This AKNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-386 amino acids from the N-terminal region of human AKNA. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AKNA Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
AKNA Antibody (N-term) - Protein Information | |
| Name AKNA | |
| Synonyms KIAA1968 | |
| Function Transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development. Binds to A/T-rich promoters | |
| Cellular Location Nucleus. | |
| Tissue Location Predominantly expressed by lymphoid tissues. Highly expressed in the spleen, lymph nodes and peripheral blood leukocytes, expressed at lower level in the thymus. Mainly expressed by germinal center B-lymphocytes, a stage in which receptor and ligand interactions are crucial for B-lymphocyte maturation. Expressed by B- and T-lymphocytes, Natural killer cells and CD1a(+)CD14(-) but not CD1a(-)CD14(+) dendritic cells Weakly or not expressed in fetal liver and in adult bone marrow | |
AKNA Antibody (N-term) - Related products
AKNA Antibody (N-term) - Application data
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AKNA Antibody (N-term) (Cat. #AP5317a) western blot analysis in Neuro-2a cell line lysates (35ug/lane).This demonstrates the AKNA antibody detected the AKNA protein (arrow).
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AKNA Antibody (N-term) (Cat. #AP5317a) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AKNA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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AKNA Antibody (N-term) (Cat. #AP5317a) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
AKNA Antibody (N-term) - Research Areas
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BACKGROUND
AKNA transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development. It binds to A/T-rich promoters.
REFERENCES
Sims-Mourtada, J.C., et al. DNA Cell Biol. 24(5):325-338(2005) Siddiqa, A., et al. Nature 410(6826):383-387(2001)
