TBKB1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | A7MCY6 |
Other Accession | Q6DG50, A2A9T0, NP_055541.1 |
Reactivity | Human, Mouse |
Predicted | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 67702 Da |
Antigen Region | 42-70 aa |
Gene ID | 9755 |
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Other Names | TANK-binding kinase 1-binding protein 1, TBK1-binding protein 1, TBKBP1 {ECO:0000312|EMBL:AAI114191} |
Target/Specificity | This TBKB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human TBKB1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TBKB1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TBKBP1 {ECO:0000312|EMBL:AAI11419.1} |
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Function | Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. |
Tissue Location | Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway
References
Ryzhakov, G., et al. EMBO J. 26(13):3180-3190(2007)
Kim, J.M., et al. DNA Res. 13(6):275-286(2006)
Bouwmeester, T., et al. Nat. Cell Biol. 6(2):97-105(2004)
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