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TBKB1 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TBKB1 Antibody  (N-term) AP5320a
    TBKB1 Antibody (N-term) (Cat. #AP5320a) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the TBKB1 antibody detected TBKB1 protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession A7MCY6
Other Accession Q6DG50, A2A9T0, NP_055541.1
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 67702 Da
Antigen Region 42-70 aa
Additional Information
Gene ID 9755
Other Names TANK-binding kinase 1-binding protein 1, TBK1-binding protein 1, TBKBP1 {ECO:0000312|EMBL:AAI114191}
Target/Specificity This TBKB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human TBKB1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTBKB1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBKBP1 {ECO:0000312|EMBL:AAI11419.1}
Function Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.
Tissue Location Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
Research Areas
Citations (0)
citation

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Background

TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway

References

Ryzhakov, G., et al. EMBO J. 26(13):3180-3190(2007)
Kim, J.M., et al. DNA Res. 13(6):275-286(2006)
Bouwmeester, T., et al. Nat. Cell Biol. 6(2):97-105(2004)

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$ 365.00
$ 140.00
Cat# AP5320a
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