|Application ||WB, ICC, IP|
|Calculated MW||130 KDa|
|Other Names||EG5;HKSP;KIF11;KIF11_HUMAN;kinesin family member 11;Kinesin like protein 1;Kinesin like spindle protein HKSP;Kinesin-like protein 1;Kinesin-like protein KIF11;Kinesin-like spindle protein HKSP;Kinesin-related motor protein Eg5;KNSL1;MCLMR;Thyroid receptor interacting protein 5;Thyroid receptor-interacting protein 5;TR-interacting protein 5; TRIP-5;TRIP5.|
|Format||Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Synonyms||EG5, KNSL1, TRIP5|
|Function||Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays.|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton, spindle pole|
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Provided below are standard protocols that you may find useful for product applications.
Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays.
Blangy A.,et al.Cell 83:1159-1169(1995).
Whitehead C.M.,et al.J. Cell Sci. 111:2551-2561(1998).
Deloukas P.,et al.Nature 429:375-381(2004).
Lee J.W.,et al.Mol. Endocrinol. 9:243-254(1995).
Beausoleil S.A.,et al.Nat. Biotechnol. 24:1285-1292(2006).
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