MRRF Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q96E11 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 29 KDa |
Antigen Region | 196-235aa |
Gene ID | 92399 |
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Other Names | Ribosome-recycling factor, mitochondrial, RRF, Ribosome-releasing factor, mitochondrial, MRRF |
Dilution | WB~~ 1:1000 |
Format | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | MRRF (HGNC:7234) |
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Function | Responsible for the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis (PubMed:19716793, PubMed:33878294). Acts in collaboration with GFM2 (PubMed:33878294). Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts (PubMed:33878294). |
Cellular Location | Mitochondrion. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity).
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Zhang Y.,et al.Biochim. Biophys. Acta 1443:245-250(1998).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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