RAB34 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9BZG1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 29 KDa |
Antigen Region | 220-259aa |
Gene ID | 83871 |
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Other Names | Ras-related protein Rab-34, Ras-related protein Rab-39, Ras-related protein Rah, RAB34, RAB39, RAH |
Dilution | WB~~ 1:1000 |
Format | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | RAB34 |
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Synonyms | RAB39, RAH |
Function | Transport protein involved in the redistribution of lysosomes to the peri-Golgi region (PubMed:27113757). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211). Plays a role in the fusion of phagosomes with lysosomes (PubMed:21255211). Involved in ciliogenesis (PubMed:37384395). Acts also as a positive regulator of hedgehog signaling and regulates ciliary function (By similarity). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q64008}. Golgi apparatus {ECO:0000250|UniProtKB:Q64008}. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Cell projection, cilium {ECO:0000250|UniProtKB:Q64008}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). |
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Background
Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
References
Hong W.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
Stanchi F.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
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