|Application ||WB, IF, IP|
|Immunogen||Purified recombinant human Jak1 protein fragments expressed in E.coli.|
|Purification||Ammonium sulfate precipitation|
|Calculated MW||130 KDa|
|Other Names||JAK 1; JAK 1A; JAK 1B; JAK-1; JAK1; JAK1_HUMAN; JAK1A; JAK1B; Janus kinase 1 (a protein tyrosine kinase); Janus kinase 1; JTK3; Tyrosine protein kinase JAK 1; Tyrosine protein kinase JAK1; Tyrosine-protein kinase JAK1.|
|Format||PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529).|
|Cellular Location||Endomembrane system; Peripheral membrane protein. Note=Wholly intracellular, possibly membrane associated|
|Tissue Location||Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.|
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Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
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