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Anti-Toll-like Receptor 7 Antibody

Mouse Anti Human Monoclonal Antibody

     
  • WB - Anti-Toll-like Receptor 7 Antibody AP53404
    Western blot detection of Toll-like Receptor 7 in CHO-K1 cell lysate(B)and CHO-K1 transfected by Toll-like Receptor 7(A)cell lysate using Toll-like Receptor 7 mouse mAb (1:1000 diluted).Predicted band size: 40KDa.Observed band size:40KDa.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9NYK1
Other Accession NM_016562
Reactivity Transfected
Host Mouse
Clonality Monoclonal
Isotype IgG1
Immunogen Purified recombinant human Toll-like Receptor protein fragments expressed in E.coli.
Purification Affinity purified
Calculated MW 120922 Da
Additional Information
Gene ID 51284
Other Names PRO285; TLR 7; Tlr7; TLR7_HUMAN ; Toll like receptor 7 ; Toll-like receptor 7; UNQ248.
Dilution WB~~1:1000
Format PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name TLR7
Function Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Cellular Location Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P58681}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P58681}. Endosome {ECO:0000250|UniProtKB:P58681}. Lysosome {ECO:0000250|UniProtKB:P58681}. Cytoplasmic vesicle, phagosome {ECO:0000250|UniProtKB:P58681}. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist {ECO:0000250|UniProtKB:P58681}
Tissue Location Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells
Research Areas
Citations (0)

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Background

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-st

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$ 295.00
Cat# AP53404
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
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