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SLC19A3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BZV2 |
| Other Accession | NP_079519.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 55665 Da |
| Antigen Region | 217-246 aa |
| Gene ID | 80704 |
|---|---|
| Other Names | Thiamine transporter 2, ThTr-2, ThTr2, Solute carrier family 19 member 3, SLC19A3 |
| Target/Specificity | This SLC19A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the Central region of human SLC19A3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SLC19A3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC19A3 |
|---|---|
| Function | Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism (PubMed:11731220, PubMed:33008889, PubMed:35512554, PubMed:35724964). Has no folate transport activity (PubMed:11731220). Mediates H(+)-dependent pyridoxine transport (PubMed:33008889, PubMed:35512554, PubMed:35724964, PubMed:36456177). |
| Cellular Location | Membrane; Multi-pass membrane protein |
| Tissue Location | Widely expressed but most abundant in placenta, kidney and liver. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
SLC19A3 encodes a ubiquitously expressed transmembrane thiamine transporter that lacks folate transport activity.
References
Mee, L., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 297 (1), G197-G206 (2009)
Liu, X., et al. Tumour Biol. 30 (5-6), 242-248 (2009)
Subramanian, V.S., et al. J. Physiol. (Lond.) 582 (PT 1), 73-85 (2007)
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