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HMGA2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - HMGA2 Antibody (C-term) AP5359b
    HMGA2 Antibody (C-term) (Cat. #AP5359b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HMGA2 antibody detected the HMGA2 protein (arrow).
  • FC - HMGA2 Antibody (C-term) AP5359b
    HMGA2 Antibody (C-term) (Cat. #AP5359b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P52926
Other Accession P52927, NP_003475.1, NP_003474.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 11832 Da
Antigen Region 64-92 aa
Additional Information
Gene ID 8091
Other Names High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC
Target/Specificity This HMGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the C-terminal region of human HMGA2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHMGA2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HMGA2
Synonyms HMGIC
Function Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes.
Cellular Location Nucleus.
Research Areas
Citations (0)

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This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.


Mu, G., et al. Hum. Pathol. 41(4):493-502(2010)
Pillas, D., et al. PLoS Genet. 6 (2), E1000856 (2010) :
Yang, T.L., et al. Ann. Hum. Genet. 74(1):11-16(2010)
Wei, J.J., et al. Am. J. Surg. Pathol. 34(1):18-26(2010)
Tay, Y., et al. Stem Cell Rev 5(4):328-333(2009)
Schwanbeck, R., et al. J. Biol. Chem. 275(3):1793-1801(2000)
Chau, K.Y., et al. Nucleic Acids Res. 23(21):4262-4266(1995)
Schoenmakers, E.F., et al. Nat. Genet. 10(4):436-444(1995)
Ashar, H.R., et al. Cell 82(1):57-65(1995)
Schoenmakers, E.F., et al. Genes Chromosomes Cancer 11(2):106-118(1994)
Manfioletti, G., et al. Nucleic Acids Res. 19(24):6793-6797(1991)

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$ 295.00
$ 99.00
Cat# AP5359b
(40 western blots)
Availability: In Stock
Bulk Size
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