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B4GALT5 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP5365b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP5365b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
B4GALT5 Antibody (C-term) - Product info | |
| Application | WB, FC
|
| Primary Accession | O43286 |
| Other Accession | Q9JMK0, NP_004767.1 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 45119 Da |
B4GALT5 Antibody (C-term) - Additional info | |
| Gene ID 9334 | |
| Other Names B4GALT5; Beta-1, 4-galactosyltransferase 5; Beta-1, 4-GalT II; UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 5 | |
| Target/Specificity This B4GALT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human B4GALT5. | |
| Dilution WB~~1:100~500WB~~1:1000 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions B4GALT5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
B4GALT5 Antibody (C-term) - Protein Information | |
| Name B4GALT5 | |
| Function Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | |
| Cellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack | |
| Tissue Location Ubiquitously expressed. | |
B4GALT5 Antibody (C-term) - Related products
B4GALT5 Antibody (C-term) - Application data
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B4GALT5 Antibody (C-term)(Cat. #AP5365b) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the B4GALT5 antibody detected B4GALT5 protein (arrow).
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B4GALT5 Antibody (C-term) (Cat. #AP5365b) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
B4GALT5 Antibody (C-term) - Research Areas
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BACKGROUND
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. This gene was previously designated as B4GALT4 but was renamed to B4GALT5. In the literature it is also referred to as beta4GalT2. [provided by RefSeq].
REFERENCES
Kitayama, K., et al. J. Biol. Chem. 282(41):30085-30096(2007) Sato, T., et al. J. Biol. Chem. 282(38):27702-27712(2007) Jiang, J., et al. J. Biol. Chem. 281(14):9482-9489(2006) Sato, T., et al. J. Biol. Chem. 279(38):39574-39583(2004) Xu, S., et al. J. Exp. Clin. Cancer Res. 21(3):409-414(2002) Deloukas, P., et al. Nature 414(6866):865-871(2001) Amado, M., et al. Biochim. Biophys. Acta 1473(1):35-53(1999) Lo, N.W., et al. Glycobiology 8(5):517-526(1998) Sato, T., et al. Biochem. Biophys. Res. Commun. 244(3):637-641(1998) Sato, T., et al. Proc. Natl. Acad. Sci. U.S.A. 95(2):472-477(1998)
