|Application ||WB, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||115155 Da|
|Antigen Region||339-367 aa|
|Other Names||Suppression of tumorigenicity 18 protein, Zinc finger protein 387, ST18, KIAA0535, ZNF387|
|Target/Specificity||This ST18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 339-367 amino acids from the N-terminal region of human ST18.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ST18 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells.|
|Tissue Location||Detected at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate Detected at even lower levels in mammary epithelial cells and breast cancer cells.|
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Provided below are standard protocols that you may find useful for product applications.
Yang, J., et al. FASEB J. 22(11):3956-3967(2008)
Jandrig, B., et al. Oncogene 23(57):9295-9302(2004)
Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :
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