ST18 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | O60284 |
Other Accession | NP_055497.1 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 115155 Da |
Antigen Region | 339-367 aa |
Gene ID | 9705 |
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Other Names | Suppression of tumorigenicity 18 protein, Zinc finger protein 387, ST18, KIAA0535, ZNF387 |
Target/Specificity | This ST18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 339-367 amino acids from the N-terminal region of human ST18. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ST18 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ST18 |
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Synonyms | KIAA0535, ZNF387 |
Function | Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells. |
Cellular Location | Nucleus. |
Tissue Location | Detected at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells |
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Provided below are standard protocols that you may find useful for product applications.
References
Yang, J., et al. FASEB J. 22(11):3956-3967(2008)
Jandrig, B., et al. Oncogene 23(57):9295-9302(2004)
Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :
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