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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TNFAIP1 Antibody (C-term)   

TNFAIP1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TNFAIP1 Antibody (C-term) AP5410b
    TNFAIP1 Antibody (C-term)(Cat. #AP5410b) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the TNFAIP1 antibody detected the TNFAIP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13829
Other Accession O70479, NP_066960.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36204 Da
Antigen Region 288-316 aa
Additional Information
Gene ID 7126
Other Names BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2, hBACURD2, BTB/POZ domain-containing protein TNFAIP1, Protein B12, Tumor necrosis factor, alpha-induced protein 1, endothelial, TNFAIP1, BACURD2, EDP1
Target/Specificity This TNFAIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-316 amino acids from the C-terminal region of human TNFAIP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTNFAIP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BACURD2, EDP1
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Cellular Location Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes
Research Areas
Citations (0)

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This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner.


Grinchuk, O.V., et al. BMC Genomics 11 SUPPL 1, S9 (2010) :
Kim, D.M., et al. Int. J. Cancer 125(11):2520-2527(2009)
Castro-Giner, F., et al. Eur. Respir. J. 33(5):1003-1009(2009)
Yang, L.P., et al. Yi Chuan 28(8):918-922(2006)
Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)
Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)
Suzuki, H., et al. Genome Res. 11(10):1758-1765(2001)
Pandey, A., et al. Science 268(5210):567-569(1995)
Wolf, F.W., et al. J. Biol. Chem. 267(2):1317-1326(1992)
Holzman, L.B., et al. Mol. Cell. Biol. 10(11):5830-5838(1990)
Dixit, V.M., et al. J. Biol. Chem. 265(5):2973-2978(1990)

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$ 295.00
$ 99.00
Cat# AP5410b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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