|Application ||WB, IHC-P, E|
|Other Accession||P62966, P62965, P40220, P62964, NP_004369.1|
|Predicted||Bovine, Chicken, Rat|
|Calculated MW||15566 Da|
|Antigen Region||90-118 aa|
|Other Names||Cellular retinoic acid-binding protein 1, Cellular retinoic acid-binding protein I, CRABP-I, CRABP1, RBP5|
|Target/Specificity||This CRABP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the C-terminal region of human CRABP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CRABP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.
Tang, X.H., et al. Exp. Cell Res. 314(1):38-51(2008)
Uhrig, M., et al. BMC Med 6, 38 (2008) :
Guidez, F., et al. Proc. Natl. Acad. Sci. U.S.A. 104(47):18694-18699(2007)
Tanaka, K., et al. Oncogene 26(44):6456-6468(2007)
Wu, Q., et al. Mol. Cancer 6, 45 (2007) :
Flagiello, D., et al. Cytogenet. Cell Genet. 76 (1-2), 17-18 (1997) :
Liu, W., et al. Biochem. Biophys. Res. Commun. 229(3):922-929(1996)
Eller, M.S., et al. Exp. Cell Res. 198(2):328-336(1992)
Astrom, A., et al. J. Biol. Chem. 266(26):17662-17666(1991)
Ong, D.E. Arch Dermatol 123 (12), 1693-1695A (1987) :
If you have any additional inquiries please email technical services at firstname.lastname@example.org.