CRLS1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q9UJA2 |
Other Accession | Q5U2V5, Q80ZM8, NP_001120930.1, NP_061968.1 |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 32593 Da |
Antigen Region | 198-226 aa |
Gene ID | 54675 |
---|---|
Other Names | Cardiolipin synthase, CLS, 278-, Protein GCD10 homolog, CRLS1, C20orf155, CLS1 |
Target/Specificity | This CRLS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human CRLS1. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CRLS1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CRLS1 |
---|---|
Synonyms | C20orf155, CLS1 |
Function | Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. |
Cellular Location | Mitochondrion inner membrane; Multi-pass membrane protein |
Tissue Location | Highly expressed in tissues such as heart, skeletal muscle and liver. |
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Provided below are standard protocols that you may find useful for product applications.
References
Garcia-Carrasco, M., et al. Clin Rev Allergy Immunol 36 (2-3), 104-108 (2009) :
Lee, J.L., et al. Clin Rev Allergy Immunol 36 (2-3), 126-130 (2009) :
Stojanovich, L., et al. Clin Rev Allergy Immunol 36 (2-3), 74-79 (2009) :
Miesbach, W. Clin Rev Allergy Immunol 36 (2-3), 91-97 (2009) :
Chen, D., et al. Biochem. J. 398(2):169-176(2006)
Lu, B., et al. J. Lipid Res. 47(6):1140-1145(2006)
Houtkooper, R.H., et al. FEBS Lett. 580(13):3059-3064(2006)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Johnson, E.M., et al. Nucleic Acids Res. 31(11):2915-2925(2003)
Deloukas, P., et al. Nature 414(6866):865-871(2001)
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