|Application ||WB, IHC-P, E|
|Other Accession||Q5U2V5, Q80ZM8, NP_001120930.1, NP_061968.1|
|Calculated MW||32593 Da|
|Antigen Region||198-226 aa|
|Other Names||Cardiolipin synthase, CLS, 278-, Protein GCD10 homolog, CRLS1, C20orf155, CLS1|
|Target/Specificity||This CRLS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human CRLS1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CRLS1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
|Tissue Location||Highly expressed in tissues such as heart, skeletal muscle and liver.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Garcia-Carrasco, M., et al. Clin Rev Allergy Immunol 36 (2-3), 104-108 (2009) :
Lee, J.L., et al. Clin Rev Allergy Immunol 36 (2-3), 126-130 (2009) :
Stojanovich, L., et al. Clin Rev Allergy Immunol 36 (2-3), 74-79 (2009) :
Miesbach, W. Clin Rev Allergy Immunol 36 (2-3), 91-97 (2009) :
Chen, D., et al. Biochem. J. 398(2):169-176(2006)
Lu, B., et al. J. Lipid Res. 47(6):1140-1145(2006)
Houtkooper, R.H., et al. FEBS Lett. 580(13):3059-3064(2006)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Johnson, E.M., et al. Nucleic Acids Res. 31(11):2915-2925(2003)
Deloukas, P., et al. Nature 414(6866):865-871(2001)
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