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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CRLS1 Antibody (C-term)   

CRLS1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CRLS1 Antibody (C-term) AP5423b
    Anti-CRLS1 Antibody (C-term) at 1:1000 dilution + T47D whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - CRLS1 Antibody (C-term) AP5423b
    CRLS1 Antibody (C-term) (Cat. #AP5423b) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CRLS1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9UJA2
Other Accession Q5U2V5, Q80ZM8, NP_001120930.1, NP_061968.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32593 Da
Antigen Region 198-226 aa
Additional Information
Gene ID 54675
Other Names Cardiolipin synthase, CLS, 278-, Protein GCD10 homolog, CRLS1, C20orf155, CLS1
Target/Specificity This CRLS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human CRLS1.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCRLS1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRLS1
Synonyms C20orf155, CLS1
Function Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein
Tissue Location Highly expressed in tissues such as heart, skeletal muscle and liver.
Research Areas
Citations (0)

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References

Garcia-Carrasco, M., et al. Clin Rev Allergy Immunol 36 (2-3), 104-108 (2009) :
Lee, J.L., et al. Clin Rev Allergy Immunol 36 (2-3), 126-130 (2009) :
Stojanovich, L., et al. Clin Rev Allergy Immunol 36 (2-3), 74-79 (2009) :
Miesbach, W. Clin Rev Allergy Immunol 36 (2-3), 91-97 (2009) :
Chen, D., et al. Biochem. J. 398(2):169-176(2006)
Lu, B., et al. J. Lipid Res. 47(6):1140-1145(2006)
Houtkooper, R.H., et al. FEBS Lett. 580(13):3059-3064(2006)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Johnson, E.M., et al. Nucleic Acids Res. 31(11):2915-2925(2003)
Deloukas, P., et al. Nature 414(6866):865-871(2001)

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$ 295.00
$ 99.00
Cat# AP5423b
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Quantity:
(40 western blots)
Availability: In Stock
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