|Application ||WB, IHC-P, FC, E|
|Calculated MW||38726 Da|
|Antigen Region||306-334 aa|
|Other Names||Transcription factor AP-4, Activating enhancer-binding protein 4, Class C basic helix-loop-helix protein 41, bHLHc41, TFAP4, BHLHC41|
|Target/Specificity||This TFAP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-334 amino acids from the C-terminal region of human TFAP4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TFAP4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that activates both viral and cellular genes by binding to the symmetrical DNA sequence 5'- CAGCTG-3'.|
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Provided below are standard protocols that you may find useful for product applications.
Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization.
Ku, W.C., et al. Mol. Cell Proteomics 8(9):2034-2050(2009)
Jung, P., et al. Proc. Natl. Acad. Sci. U.S.A. 105(39):15046-15051(2008)
Pons, J., et al. Biochemistry 47(1):14-29(2008)
Mermod, N., et al. Nature 332(6164):557-561(1988)
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