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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SPT13 Antibody (Center)   

SPT13 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SPT13 Antibody (Center) AP5504c
    SPT13 Antibody (Center) (Cat.#AP5504c) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SPT13 antibody detected the SPT13 protein (arrow).
  • IHC-P - SPT13 Antibody (Center) AP5504c
    SPT13 Antibody (Center) (Cat. #AP5504c) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SPT13 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - SPT13 Antibody (Center) AP5504c
    SPT13 Antibody (Center) (Cat. #AP5504c) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96N96
Other Accession NP_694568.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 74820 Da
Antigen Region 204-232 aa
Additional Information
Gene ID 221178
Other Names Spermatogenesis-associated protein 13, APC-stimulated guanine nucleotide exchange factor 2, Asef2, SPATA13
Target/Specificity This SPT13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the Central region of human SPT13.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSPT13 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPATA13
Function Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up- regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
Cellular Location Cytoplasm. Cell projection, filopodium. Cell projection, lamellipodium. Cell projection, ruffle membrane Note=Accumulates in the lamellipodium and ruffle membrane in response to hepatocyte growth factor (HGF) treatment
Tissue Location Expressed at high levels in the placenta, spleen and kidney, at moderate levels in lung, small intestine, liver, brain and heart, and at low levels in skeletal muscle Expression is aberrantly enhanced in most colorectal tumors
Research Areas
Citations (0)

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The function of SPT13 remains unknown.


Ding, H., et al. Stroke 41(1):177-180(2010)
Bristow, J.M., et al. J. Cell. Sci. 122 (PT 24), 4535-4546 (2009)
Sagara, M., et al. Oncogene 28(10):1357-1365(2009)

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$ 295.00
$ 99.00
Cat# AP5504c
(40 western blots)
Availability: In Stock
Bulk Size
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