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DDC Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DDC Antibody (N-term) AP5536a
    Anti-DDC Antibody (N-term) at 1:1000 dilution + human kidney lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 54 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IF - DDC Antibody (N-term) AP5536a
    Confocal immunofluorescent analysis of DDC Antibody (N-term)(Cat#AP5536a) with HepG2 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
  • WB - DDC Antibody (N-term) AP5536a
    DDC Antibody (N-term) (Cat. #AP5536a) western blot analysis in mouse liver,kidney tissue lysates (15ug/lane).This demonstrates the DDC antibody detected DDC protein (arrow).
  • IHC-P - DDC Antibody (N-term) AP5536a
    DDC Antibody (N-term) (Cat. #AP5536a) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DDC Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - DDC Antibody (N-term) AP5536a
    DDC Antibody (N-term) (Cat. #AP5536a) flow cytometric analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P20711
Other Accession NP_000781.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53926 Da
Antigen Region 32-61 aa
Additional Information
Gene ID 1644
Other Names Aromatic-L-amino-acid decarboxylase, AADC, DOPA decarboxylase, DDC, DDC, AADC
Target/Specificity This DDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human DDC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDDC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DDC
Synonyms AADC
Function Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
Research Areas
Citations (0)

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This protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency.


Kokkinou, I., et al. J. Neuroimmunol. 216 (1-2), 51-58 (2009) : Meda, S.A., et al. Neuroimage (2009) Ishikawa, S., et al. J. Biol. Chem. 284(42):28832-28844(2009) Trevino, L.R., et al. Nat. Genet. 41(9):1001-1005(2009)

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$ 295.00
$ 99.00
Cat# AP5536a
(40 western blots)
Availability: In Stock
Bulk Size
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