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TSPAN3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TSPAN3 Antibody (Center) AP5559c
    TSPAN3 Antibody (Center) (Cat. #AP5559c) western blot analysis in mouse kidney tissue lysates (15ug/lane).This demonstrates the TSPAN3 antibody detected TSPAN3 protein (arrow).
  • IHC-P - TSPAN3 Antibody (Center) AP5559c
    TSPAN3 Antibody (Center) (Cat. #AP5559c) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TSPAN3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - TSPAN3 Antibody (Center) AP5559c
    TSPAN3 Antibody (Center) (Cat. #AP5559c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60637
Other Accession Q9QY33, Q3SZR9, NP_005715.1
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28018 Da
Antigen Region 90-117 aa
Additional Information
Gene ID 10099
Other Names Tetraspanin-3, Tspan-3, Tetraspanin TM4-A, Transmembrane 4 superfamily member 8, TSPAN3, TM4SF8
Target/Specificity This TSPAN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 amino acids from the Central region of human TSPAN3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTSPAN3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TM4SF8
Function Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.
Cellular Location Membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene.


Berditchevski, F. J. Cell. Sci. 114 (PT 23), 4143-4151 (2001) :
Todd, S.C., et al. Biochim. Biophys. Acta 1399(1):101-104(1998)
Wu, Y.J., et al. J. Biol. Chem. 266(26):17566-17572(1991)

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Cat# AP5559c
(40 western blots)
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