|Application ||WB, IHC-P, E|
|Other Accession||A0JN80, NP_001137160.1|
|Calculated MW||120787 Da|
|Antigen Region||195-224 aa|
|Other Names||DIS3-like exonuclease 1, 3113-, DIS3L, DIS3L1, KIAA1955|
|Target/Specificity||This DI3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-224 amino acids from the N-terminal region of human DI3L1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DI3L1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
DIS3L is a probable exonuclease. It has four isoforms.
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.