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DI3L1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DI3L1 Antibody  (N-term) AP5614a
    DI3L1 Antibody (N-term) (Cat. #AP5614a) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the DI3L1 antibody detected DI3L1 protein (arrow).
  • IHC-P - DI3L1 Antibody  (N-term) AP5614a
    DI3L1 Antibody (N-term) (Cat. #AP5614a) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DI3L1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TF46
Other Accession A0JN80, NP_001137160.1
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 120787 Da
Antigen Region 195-224 aa
Additional Information
Gene ID 115752
Other Names DIS3-like exonuclease 1, 3113-, DIS3L, DIS3L1, KIAA1955
Target/Specificity This DI3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-224 amino acids from the N-terminal region of human DI3L1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDI3L1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DIS3L
Synonyms DIS3L1, KIAA1955
Function Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
Cellular Location Cytoplasm
Research Areas
Citations (0)

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DIS3L is a probable exonuclease. It has four isoforms.


Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)

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Cat# AP5614a
(40 western blots)
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