|Application ||WB, FC, E|
|Calculated MW||128697 Da|
|Antigen Region||1076-1104 aa|
|Other Names||Protein transport protein Sec31B, SEC31-like protein 2, SEC31-related protein B, SEC31B-1, SEC31B, SEC31L2|
|Target/Specificity||This SC31B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1076-1104 amino acids from the C-terminal region of human SC31B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SC31B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum.|
|Cellular Location||Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein|
|Tissue Location||Ubiquitously expressed at low levels with specific expression in thymus and testis. Expressed in testis by Sertoli cells, Leydig cells and spermatogonia and in cerebellum more prominently by Purkinje and granular cells (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein of unknown function. The protein has moderate similarity to rat VAP1 protein which is an endosomal membrane-associated protein, containing a putative Ca2+/calmodulin-dependent kinase II phosphorylation site.
Stankewich, M.C., et al. J. Cell. Sci. 119 (PT 5), 958-969 (2006) :
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Tang, B.L., et al. J. Biol. Chem. 275(18):13597-13604(2000)
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