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ACOT2 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP5652c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP5652c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ACOT2 Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | P49753 |
| Other Accession | Q86TX2, NP_006812.3 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 53218 Da |
ACOT2 Antibody (Center) - Additional info | |
| Gene ID 10965 | |
| Other Names ACOT2; PTE2; PTE2A; Acyl-coenzyme A thioesterase 2, mitochondrial; Acyl-coenzyme A thioester hydrolase 2a; CTE-Ia; Long-chain acyl-CoA thioesterase 2; ZAP128 | |
| Target/Specificity This ACOT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the Central region of human ACOT2. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ACOT2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ACOT2 Antibody (Center) - Protein Information | |
| Name ACOT2 | |
| Synonyms PTE2, PTE2A | |
| Function Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH Displays high levels of activity on medium- and long chain acyl CoAs | |
| Cellular Location Mitochondrion. | |
| Tissue Location Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas | |
ACOT2 Antibody (Center) - Related products
AP5301c: ZAP128 Antibody (Center)
AP5652c: ACOT2 Antibody (Center)
ACOT2 Antibody (Center) - Application data
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ACOT2 Antibody (Center) (Cat. #AP5652c) western blot analysis in MDA-MB435,NCI-H460 cell line lysates (15ug/lane).This demonstrates the ACOT2 antibody detected the ACOT2 protein (arrow).
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ACOT2 Antibody (Center) (Cat. #AP5652c) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ACOT2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
ACOT2 Antibody (Center) - Research Areas
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BACKGROUND
Acyl-CoA thioesterases, such as ACOT2, are a group of enzymes that hydrolyze CoA esters, such as acyl-CoAs, bile CoAs, and CoA esters of prostaglandins, to the corresponding free acid and CoA (Hunt et al., 2005 [PubMed 16103133]).
REFERENCES
Mandel, C.R., et al. Biochem. Biophys. Res. Commun. 385(4):630-633(2009) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Hunt, M.C., et al. FASEB J. 20(11):1855-1864(2006)