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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SLC4A7 Antibody (C-term)   

SLC4A7 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SLC4A7 Antibody (C-term) AP5655B
    SLC4A7 Antibody (C-term) (Cat. #AP5655b) western blot analysis in K562 cell line lysates (15ug/lane).This demonstrates the SLC4A7 antibody detected the SLC4A7 protein (arrow).
  • IHC-P - SLC4A7 Antibody (C-term) AP5655B
    SLC4A7 Antibody (C-term) (Cat. #AP5655b) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SLC4A7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y6M7
Other Accession NP_003606.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 136044 Da
Antigen Region 1186-1214 aa
Additional Information
Gene ID 9497
Other Names Sodium bicarbonate cotransporter 3, Electroneutral Na/HCO(3) cotransporter, Sodium bicarbonate cotransporter 2, Sodium bicarbonate cotransporter 2b, Bicarbonate transporter, Solute carrier family 4 member 7, SLC4A7, BT, NBC2, NBC2B, NBC3, NBCn1, SBC2, SLC4A6
Target/Specificity This SLC4A7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1186-1214 amino acids from the C-terminal region of human SLC4A7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLC4A7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC4A7
Synonyms BT, NBC2, NBC2B, NBC3, NBCn1, SBC2, SLC4
Function Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarbonate salvage in secretory epithelia. May also have an associated sodium channel activity.
Cellular Location Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell projection, stereocilium. Note=Also described at the apical cell membrane Localizes to the stereocilia of cochlear outer hair cells and to the lateral membrane of cochlear inner hair cells (By similarity)
Tissue Location Highly expressed in testis and spleen. Also expressed in retina, colon, small intestine, ovary, thymus, prostate, muscle, heart and kidney. Isoform 1 is expressed in skeletal muscle and heart muscle.
Research Areas
Citations (0)

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SLC4A7 regulates intracellular pH and may also play a role in bicarbonate salvage in secretory epithelia. Additionally, SLC4A7 may also have associated sodium channel activity.


Odefrey, F., et al. Cancer Res. 70(4):1449-1458(2010)
Ahmed, S., et al. Nat. Genet. 41(5):585-590(2009)
Ishiguro, H., et al. Addiction 102(8):1320-1325(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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Cat# AP5655B
(40 western blots)
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