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ADCYAP1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ADCYAP1 Antibody (C-term) AP5668B
    ADCYAP1 Antibody (C-term) (Cat. #AP5668b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ADCYAP1 antibody detected the ADCYAP1 protein (arrow).
  • IHC-P - ADCYAP1 Antibody (C-term) AP5668B
    ADCYAP1 Antibody (C-term) (Cat. #AP5668b) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ADCYAP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - ADCYAP1 Antibody (C-term) AP5668B
    Confocal immunofluorescent analysis of ADCYAP1 Antibody (C-term) (Cat. #AP5668b) with 293 cell followed by Alexa Fluor搴?488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
  • FC - ADCYAP1 Antibody (C-term) AP5668B
    ADCYAP1 Antibody (C-term) (Cat. #AP5668b) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P18509
Other Accession P13589, P41535, O70176, NP_001093203.1
Reactivity Human
Predicted Mouse, Rat, Pig
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 18835 Da
Antigen Region 148-176 aa
Additional Information
Gene ID 116
Other Names Pituitary adenylate cyclase-activating polypeptide, PACAP, PACAP-related peptide, PRP-48, Pituitary adenylate cyclase-activating polypeptide 27, PACAP-27, PACAP27, Pituitary adenylate cyclase-activating polypeptide 38, PACAP-38, PACAP38, ADCYAP1
Target/Specificity This ADCYAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human ADCYAP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsADCYAP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway.
Cellular Location Secreted.
Research Areas
Citations (0)

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ADCYAP1 is adenylate cyclase activating polypeptide 1. Mediated by adenylate cyclase activating polypeptide 1 receptors, this polypeptide stimulates adenylate cyclase and subsequently increases the cAMP level in target cells. Adenylate cyclase activating polypeptide 1 is not only a hypophysiotropic hormone, but also functions as a neurotransmitter and neuromodulator. In addition, it plays a role in paracrine and autocrine regulation of certain types of cells. This gene encodes three different mature peptides, including two isotypes, a shorter form and a longer form.


Hosoya, M., et al. Biochim. Biophys. Acta 1129(2):199-206(1992)
Ohkubo, S., et al. DNA Cell Biol. 11(1):21-30(1992)
Kimura, C., et al. Biochem. Biophys. Res. Commun. 166(1):81-89(1990)

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Cat# AP5668B
(40 western blots)
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