|Application ||WB, IHC-P, E|
|Calculated MW||184281 Da|
|Antigen Region||1165-1193 aa|
|Other Names||Sterile alpha motif domain-containing protein 9, SAM domain-containing protein 9, SAMD9, C7orf5, DRIF1, KIAA2004, OEF1|
|Target/Specificity||This SAMD9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1165-1193 amino acids from the C-terminal region of human SAMD9.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SAMD9 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C7orf5, DRIF1, KIAA2004, OEF1|
|Function||May play a role in the inflammatory response to tissue injury and the control of extra-osseous calcification, acting as a downstream target of TNF-alpha signaling. Involved in the regulation of EGR1, in coordination with RGL2. May be involved in endosome fusion.|
|Tissue Location||Widely expressed. Very low levels are detected in skeletal muscle. Not detected in brain. Down-regulated in aggressive fibromatosis, as well as in breast and colon cancers Up-regulated in fibroblasts from patients with normophosphatemic tumoral calcinosis (NFTC).|
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Provided below are standard protocols that you may find useful for product applications.
Tanaka, M., et al. Int. J. Cancer 126(8):1982-1991(2010)
Chefetz, I., et al. J. Invest. Dermatol. 128(6):1423-1429(2008)
Dereure, O. Ann Dermatol Venereol 134 (5 PT 1), 505 (2007) :
Li, C.F., et al. BMC Genomics 8, 92 (2007) :
Topaz, O., et al. Am. J. Hum. Genet. 79(4):759-764(2006)
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