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BRWD2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - BRWD2 Antibody (Center) AP5715c
    BRWD2 Antibody (Center) (Cat. #AP5715c) western blot analysis in mouse testis tissue lysates (15ug/lane).This demonstrates the BRWD2 antibody detected BRWD2 protein (arrow).
  • FC - BRWD2 Antibody (Center) AP5715c
    BRWD2 Antibody (Center) (Cat. #AP5715c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BZH6
Other Accession NP_060587.8
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 136685 Da
Antigen Region 544-572 aa
Additional Information
Gene ID 55717
Other Names WD repeat-containing protein 11, Bromodomain and WD repeat-containing protein 2, WD repeat-containing protein 15, WDR11, BRWD2, KIAA1351, WDR15
Target/Specificity This BRWD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544-572 amino acids from the Central region of human BRWD2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBRWD2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDR11
Synonyms BRWD2, KIAA1351, WDR15
Cellular Location Membrane; Single-pass membrane protein. Cytoplasm Nucleus. Note=Might be shuttling between the nucleus and the cytoplasm
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.


Katoh, M., et al. Int. J. Mol. Med. 11(5):579-583(2003)
Katoh, M., et al. Int. J. Oncol. 22(5):1155-1159(2003)
Chernova, O.B., et al. Oncogene 20(38):5378-5392(2001)

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Cat# AP5715c
(40 western blots)
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