PGAP2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, WB, E |
---|---|
Primary Accession | Q9UHJ9 |
Other Accession | Q2ABP3, Q3TQR0, Q2ABP2, NP_001138910.1 |
Reactivity | Human |
Predicted | Hamster, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 29400 Da |
Antigen Region | 214-242 aa |
Gene ID | 27315 |
---|---|
Other Names | Post-GPI attachment to proteins factor 2, FGF receptor-activating protein 1, PGAP2, FRAG1 |
Target/Specificity | This PGAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the C-terminal region of human PGAP2. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PGAP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PGAP2 (HGNC:17893) |
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Synonyms | FRAG1 |
Function | Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface. |
Cellular Location | Golgi apparatus membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein |
Tissue Location | Ubiquitously expressed, with highest levels in testis and pancreas. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PGAP2 is involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similarity).
References
Tashima, Y., et al. Mol. Biol. Cell 17(3):1410-1420(2006)
Lorenzi, M.V., et al. Genomics 62(1):59-66(1999)
Robertson, N.G., et al. Genomics 23(1):42-50(1994)
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