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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   HRASLS3 Antibody (C-term)   

HRASLS3 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HRASLS3 Antibody (C-term) AP5747a
    HRASLS3 Antibody (C-term) (Cat. #AP5747a) western blot analysis in mouse kidney tissue lysates (15ug/lane).This demonstrates the HRASLS3 antibody detected HRASLS3 protein (arrow).
  • FC - HRASLS3 Antibody (C-term) AP5747a
    HRASLS3 Antibody (C-term) (Cat. #AP5747a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P53816
Other Accession NP_009000
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 17937 Da
Antigen Region 104-132 aa
Additional Information
Gene ID 11145
Other Names HRAS-like suppressor 3, HRSL3, Adipose-specific phospholipase A2, AdPLA, Group XVI phospholipase A1/A2, H-rev 107 protein homolog, HRAS-like suppressor 1, HREV107-1, HREV107-3, Renal carcinoma antigen NY-REN-65, PLA2G16, HRASLS3, HREV107
Target/Specificity This HRASLS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-132 amino acids from the C-terminal region of human HRASLS3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHRASLS3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLA2G16
Synonyms HRASLS3, HREV107
Function Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O- acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.
Cellular Location Cytoplasm. Cytoplasm, perinuclear region. Membrane; Single-pass membrane protein
Tissue Location Widely expressed. low expression, if any, in hematopoietic cells and thymus. In testis, confined to round spermatids. Expressed in normal ovarian epithelial cells. Down- regulated in some ovarian carcinomas and testicular germ cell tumors.
Research Areas
Citations (0)

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PLA2G16 specifically catalyzes the release of fatty acids from phospholipids in adipose tissue. It also has a weak lysophospholipase activity (By similarity). Tumor suppressor that may be involved in interferon-dependent cell death.


Uyama, T., et al. Biochim. Biophys. Acta 1791(12):1114-1124(2009)
Duncan, R.E., et al. J. Biol. Chem. 283(37):25428-25436(2008)
Nazarenko, I., et al. J. Cell. Sci. 120 (PT 8), 1393-1404 (2007)
Nazarenko, I., et al. Am. J. Pathol. 169(4):1427-1439(2006)

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Cat# AP5747a
(40 western blots)
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