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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   KIR2DL2 Antibody (C-Term)   

KIR2DL2 Antibody (C-Term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KIR2DL2 Antibody (C-Term) AP5762d
    KIR2DL2 Antibody (C-Term) (Cat. #AP5762d) western blot analysis in MDA-MB231,Jurkat cell line lysates (35ug/lane).This demonstrates the KIR2DL2 antibody detected the KIR2DL2 protein (arrow).
  • FC - KIR2DL2 Antibody (C-Term) AP5762d
    KIR2DL2 Antibody (C-Term) (Cat. #AP5762d) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P43627
Other Accession P43626, NP_055034.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 38472 Da
Antigen Region 263-291 aa
Additional Information
Gene ID 3803
Other Names Killer cell immunoglobulin-like receptor 2DL2, CD158 antigen-like family member B1, MHC class I NK cell receptor, Natural killer-associated transcript 6, NKAT-6, p58 natural killer cell receptor clone CL-43, p58 NK receptor CL-43, CD158b1, KIR2DL2, CD158B1, NKAT6
Target/Specificity This KIR2DL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-291 amino acids from the C-terminal region of human KIR2DL2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKIR2DL2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KIR2DL2
Synonyms CD158B1, NKAT6
Function Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.


Jiao, Y.L., et al. J. Clin. Immunol. 30(6):840-844(2010) Zhu, B.F., et al. Hum. Immunol. 71(11):1116-1123(2010) Gao, X., et al. Clin. Immunol. 137(1):139-146(2010) Al Omar, S., et al. Hum. Immunol. 71(10):976-981(2010) Velickovic, M., et al. Tissue Antigens (2010) In press :

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$ 295.00
$ 99.00
Cat# AP5762d
(40 western blots)
Availability: In Stock
Bulk Size
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