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>   home   >   Products   >   Primary Antibodies   >   Z385B Antibody (N-term)   

Z385B Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Z385B Antibody  (N-term) AP5790b
    Z385B Antibody (N-term) (Cat. #AP5790b) western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the Z385B antibody detected the Z385B protein (arrow).
  • IHC-P - Z385B Antibody  (N-term) AP5790b
    Z385B Antibody (N-term) (Cat. #AP5790b) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Z385B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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  • CITATIONS: 1
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q569K4
Other Accession NP_689733.3
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Antigen Region 1-30 aa
Additional Information
Other Names Zinc finger protein 385B, Zinc finger protein 533, ZNF385B, ZNF533
Target/Specificity This Z385B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids of human Z385B.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZ385B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZNF385B
Synonyms ZNF533
Function May play a role in p53/TP53-mediated apoptosis.
Cellular Location Nucleus.
Tissue Location Detected in germinal center of lymph node (at protein level). Expressed in spleen, lymph node and tonsil EMBL; AK057999; BAB71629.1; -; mRNA EMBL; AK096822; BAC04870.1; -; mRNA EMBL; AK131432; BAD18578.1; -; mRNA EMBL; BC038422; AAH38422.1; -; mRNA EMBL; BC048123; AAH48123.1; -; mRNA EMBL; BC092423; AAH92423.1; -; mRNA CCDS; CCDS46463.1; -. [Q569K4-2] CCDS; CCDS46464.1; -. [Q569K4-3] RefSeq; NP_001106868.1; NM_001113397.1. [Q569K4-2] RefSeq; NP_001106869.1; NM_001113398.1. [Q569K4-3] RefSeq; NP_001269654.1; NM_001282725.1. [Q569K4-3] RefSeq; NP_689733.3; NM_152520.4 RefSeq; XP_016858927.1; XM_017003438.1. [Q569K4-3] RefSeq; XP_016858928.1; XM_017003439.1. [Q569K4-3] UniGene; Hs.655005; - ProteinModelPortal; Q569K4; - BioGrid; 127344; 3 STRING; 9606.ENSP00000386845; - iPTMnet; Q569K4; - PhosphoSitePlus; Q569K4; - BioMuta; ZNF385B; - DMDM; 74741028; - PaxDb; Q569K4; - PeptideAtlas; Q569K4; - PRIDE; Q569K4; - ProteomicsDB; 62574; - ProteomicsDB; 62575; -. [Q569K4-2] ProteomicsDB; 62576; -. [Q569K4-3] ProteomicsDB; 62577; -. [Q569K4-4] ProteomicsDB; 62578; -. [Q569K4-5] DNASU; 151126; - Ensembl; ENST00000336917; ENSP00000338225; ENSG00000144331. [Q569K4-3] Ensembl; ENST00000409343; ENSP00000386379; ENSG00000144331. [Q569K4-2] Ensembl; ENST00000409692; ENSP00000386507; ENSG00000144331. [Q569K4-3] Ensembl; ENST00000644742; ENSP00000494328; ENSG00000144331. [Q569K4-1] GeneID; 151126; - KEGG; hsa:151126; - UCSC; uc002unj.4; human. [Q569K4-1] CTD; 151126; - DisGeNET; 151126; - EuPathDB; HostDB:ENSG00000144331.18; - GeneCards; ZNF385B; - HGNC; HGNC:26332; ZNF385B HPA; HPA046086; - MIM; 612344; gene neXtProt; NX_Q569K4; - OpenTargets; ENSG00000144331; - PharmGKB; PA162410114; - eggNOG; ENOG410IHAD; Eukaryota eggNOG; ENOG410Y1ZH; LUCA GeneTree; ENSGT00390000002371; - HOGENOM; HOG000231865; - HOVERGEN; HBG054524; - InParanoid; Q569K4; - OMA; QKDMIKP; - OrthoDB; EOG091G089X; - PhylomeDB; Q569K4; - TreeFam; TF326622; - ChiTaRS; ZNF385B; human GenomeRNAi; 151126; - PRO; PR:Q569K4; - Proteomes; UP000005640; Chromosome 2 Bgee; ENSG00000144331; - CleanEx; HS_ZNF385B; - ExpressionAtlas; Q569K4; baseline and differential Genevisible; Q569K4; HS GO; GO:0001650; C:fibrillar center; IDA:HPA GO; GO:0005634; C:nucleus; IDA:UniProtKB GO; GO:0002039; F:p53 binding; IPI:UniProtKB GO; GO:0003723; F:RNA binding; IBA:GO_Central GO; GO:0008270; F:zinc ion binding; IEA:InterPro GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IDA:UniProtKB InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2 InterPro; IPR036236; Znf_C2H2_sf InterPro; IPR013087; Znf_C2H2_type SMART; SM00355; ZnF_C2H2; 4 SMART; SM00451; ZnF_U1; 4 SUPFAM; SSF57667; SSF57667; 4 1: Evidence at protein level; Alternative splicing; Apoptosis; Complete proteome; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Zinc; Zinc-finger CHAIN 1 471 Zinc finger protein 385B /FTId=PRO_0000191812 ZN_FING 34 64 Matrin-type 1 ZN_FING 157 187 Matrin-type 2 ZN_FING 282 316 Matrin-type 3 ZN_FING 348 378 Matrin-type 4 REGION 1 93 Required for induction of apoptosis REGION 94 471 Interaction with p53/TP53 VAR_SEQ 1 196 Missing (in isoform 4) /FTId=VSP_015972 VAR_SEQ 1 102 Missing (in isoform 3) /FTId=VSP_015973 VAR_SEQ 1 76 Missing (in isoform 2) /FTId=VSP_015974 VAR_SEQ 1 1 M -> MRYSLSPDNHLEDGIM (in isoform 5) /FTId=VSP_015975 VAR_SEQ 77 84 SPSSNSST -> MWSGLPSR (in isoform 2) /FTId=VSP_015976 VAR_SEQ 366 368 HIS -> PKA (in isoform 4) /FTId=VSP_015977 VAR_SEQ 369 471 Missing (in isoform 4) /FTId=VSP_015978 VAR_SEQ 386 406 SPYNKLQRSPSILAAKLAFQK -> TPCKVIGLLPKPLPPA NRQLS (in isoform 5) /FTId=VSP_015979 VAR_SEQ 407 471 Missing (in isoform 5) /FTId=VSP_015980 VARIANT 242 242 S -> G (in dbSNP:rs2271761) /FTId=VAR_053765 VARIANT 416 416 F -> Y. /FTId=VAR_076447 CONFLICT 254 254 L -> P (in Ref. 1; BAB71629) CONFLICT 415 415 A -> S (in Ref. 1; BAC04870) SEQUENCE 471 AA; 50407 MW; 052813B99B908515 CRC64; MNMANFLRGF EEKGIKNDRP EDQLSKEKKK ILFSFCEVCN IQLNSAAQAQ VHSNGKSHRK RVKQLSDGQP PPPAQASPSS NSSTGSTCHT TTLPALVRTP TLMMQPSLDI KPFMSFPVDS SSAVGLFPNF NTMDPVQKAV INHTFGVSIP PKKKQVISCN VCQLRFNSDS QAEAHYKGSK HAKKVKALDA TKNKPKMVPS KDSAKANPSC SITPITGNNS DKSEDKGKLK ASSSSQPSSS ESGSFLLKSG TTPLPPGAAT SPSKSTNGAP GTVVESEEEK AKKLLYCSLC KVAVNSLSQL EAHNTGSKHK TMVEARNGAG PIKSYPRPGS RLKMQNGSKG SGLQNKTFHC EICDVHVNSE IQLKQHISSR RHKDRVAGKP LKPKYSPYNK LQRSPSILAA KLAFQKDMMK PLAPAFLSSP LAAAAAVSSA LSLPPRPSAS LFQAPAIPPA LLRPGHGPIR ATPASILFAP Y
Citations ( 0 )

Background

ZNF385B contains 4 U1-type zinc fingers. ZNF385B is expressed in brain with a potential role in RNA maturation, stability, or transcription regulation. There are 5 known isoforms.

References

Maestrini, E., et al. Mol. Psychiatry (2009) In press : Trynka, G., et al. Gut (2009) In press :

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$ 295.00
$ 99.00
Cat# AP5790b
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