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C4orf31 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - C4orf31 Antibody (N-term) AP5812a
    C4orf31 Antibody (N-term) (Cat. #AP5812a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the C4orf31 antibody detected the C4orf31 protein (arrow).
    detail
  • IHC-P - C4orf31 Antibody (N-term) AP5812a
    C4orf31 Antibody (N-term) (Cat. #AP5812a) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the C4orf31 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • FC - C4orf31 Antibody (N-term) AP5812a
    C4orf31 Antibody (N-term) (Cat. #AP5812a) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, WB, IHC-P, E
Primary Accession Q8TB73
Other Accession NP_078850.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 64673 Da
Antigen Region 80-109 aa
Additional Information
Gene ID 79625
Other Names Protein NDNF, Neuron-derived neurotrophic factor, NDNF, C4orf31
Target/Specificity This C4orf31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids of human C4orf31.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsC4orf31 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NDNF
Synonyms C4orf31
Function Secretory protein that plays a role in various cellular processes (PubMed:20969804, PubMed:24706764, PubMed:31883645). Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus (PubMed:31883645). Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system (PubMed:20969804, PubMed:31883645). May also act through the regulation of growth factors activity and downstream signaling (PubMed:31883645). Also regulates extracellular matrix assembly and cell adhesiveness (By similarity). Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms (PubMed:24706764).
Cellular Location Secreted
Tissue Location Expressed in neurons along the gonadotropin- releasing hormone (GnRH) expressing neurons migratory route
Research Areas
Citations ( 0 )

Background

Promotes matrix assembly and cell adhesiveness (By similarity).

References

Utine, G.E., et al. Genet. Couns. 17(2):205-209(2006) Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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$ 365.00
$ 140.00
Cat# AP5812a
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