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> home > Products > Primary Antibodies > Antibody Collections > Catalog Updated > hCG_2039146 Antibody (Center)
hCG_2039146 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | A6NL88 |
| Other Accession | Q8C3Q5, NP_001138648.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 56214 Da |
| Antigen Region | 308-337 aa |
| Gene ID | 729956 |
|---|---|
| Other Names | Protein shisa-7, Protein shisa-6-like, SHISA7 |
| Target/Specificity | This hCG_2039146 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the Central region of human hCG_2039146. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | hCG_2039146 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SHISA7 (HGNC:35409) |
|---|---|
| Function | Transmembrane protein that regulates gamma-aminobutyric acid type A receptor (GABA(A)R) trafficking, channel deactivation kinetics and pharmacology, necessary for fast inhibitory transmission in the brain. Enhances the action of benzodiazepine, a primary GABA(A)Rs target drug, in the brain. May affect channel kinetics of AMPA-type glutamate receptors (AMPAR), the brain's main excitatory neurotransmitter, necessary for synaptic hippocampal plasticity, and memory recall. May regulate the induction and maintenance of long-term potentiation at Schaffer collaterals/CA3-CA1 excitatory synapses. |
| Cellular Location | Postsynaptic density membrane {ECO:0000250|UniProtKB:Q8C3Q5}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q8C3Q5}. Note=Localizes at GABAergic inhibitory synapses and colocalizes with gephyrin in hippocampal neurons {ECO:0000250|UniProtKB:Q8C3Q5} |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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$ 365.00
$ 140.00
Cat# AP5815c
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