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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FGF2-T254 Antibody   

FGF2-T254 Antibody

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FGF2-T254 Antibody AP5826A
    FGF2 Antibody (Cat. #AP5826a) western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the FGF2 antibody detected FGF2 protein (arrow).
  • IHC-P - FGF2-T254 Antibody AP5826A
    FGF2-T254 antibody (Cat. #AP5826a)immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FGF2-T254 antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09038
Other Accession NP_001997.5
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 30770 Da
Antigen Region 232-261 aa
Additional Information
Gene ID 2247
Other Names Fibroblast growth factor 2, FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2, FGF2, FGFB
Target/Specificity This FGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from human FGF2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFGF2-T254 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FGF2
Synonyms FGFB
Function Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
Cellular Location Secreted. Nucleus. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane. Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57
Tissue Location Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue.
Research Areas
Citations ( 0 )
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Cat# AP5826A
(40 western blots)
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