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> home > Products > Antibodies > Biological Process > Regulation Of Protein Metabolic Process > PUM2-S136 Antibody
PUM2-S136 AntibodyPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP5827a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP5827a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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PUM2-S136 Antibody - Product info | |
| Application | WB, FC
|
| Primary Accession | Q8TB72 |
| Other Accession | Q80U58, NP_056132.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 114216 Da |
PUM2-S136 Antibody - Additional info | |
| Gene ID 23369 | |
| Other Names PUM2; KIAA0235; PUMH2; Pumilio homolog 2 | |
| Target/Specificity This PUM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-150 amino acids from human PUM2. | |
| Dilution WB~~1:100~500WB~~1:1000 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions PUM2-S136 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
PUM2-S136 Antibody - Protein Information | |
| Name PUM2 | |
| Synonyms KIAA0235, PUMH2 | |
| Function Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts | |
| Cellular Location Cytoplasm (Probable). Cytoplasmic granule (By similarity). Cytoplasm, perinuclear region. Note=The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Co-localizes with NANOS3 in the stress granules (By similarity). Co-localizes with NANOS1 and SNAPIN in the perinuclear region of germ cells | |
| Tissue Location Expressed in male germ cells of adult testis (at protein level). Highly expressed in testis and ovary Predominantly expressed in stem cells and germ cells. Expressed at lower level in brain, heart, kidney, liver, muscle, placenta, intestine and stomach Expressed in cerebellum, corpus callosum, caudate nucleus, hippocampus, medulla oblongata and putamen Expressed in all fetal tissues tested | |
PUM2-S136 Antibody - Related products
AP3721a: Phospho-PUM2- S182 Antibody
AP3733a: Phospho-PUM2- S136 Antibody
AP7569b: PUM2 Antibody (N-term)
BP3721a: Phospho-PUM2-S182 Antibody Blocking Peptide
BP3733a: Phospho-PUM2-S136 Antibody Blocking peptide
BP5827a: PUM2-S136 Antibody Blocking peptide
PUM2-S136 Antibody - Application data
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PUM2-S136 Antibody (Cat. #AP5827a) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the PUM2 antibody detected the PUM2 protein (arrow).
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PUM2-S136 Antibody (Cat. #AP5827a) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
PUM2-S136 Antibody - Research Areas
AntibodiesBiological ProcessRegulation Of Protein Metabolic ProcessRegulation Of Cellular Protein Metabolic ProcessRegulation Of Metabolic ProcessRegulation Of Cellular Metabolic ProcessBiological RegulationRegulation Of Macromolecule Metabolic ProcessRegulation Of Primary Metabolic ProcessRegulation Of Biological ProcessRegulation Of Cellular ProcessPosttranscriptional Regulation Of Gene ExpressionCellular CompartmentCytoplasmIntracellular PartIntracellularMolecular FunctionProtein BindingTissueBrianLungPlacentaEpithelium
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