|Application ||WB, IHC-P, E|
|Other Accession||Q9JJL4, Q8R527, Q8BYP3, Q9HBH0, Q3SZA1, Q62159, P08134, Q9PSX7, Q1RMJ6, P62747, P62746, P62745, Q3ZBW5, P61589, Q9QUI0, P61586, P61585, P53879, P06780, P48148, Q22038, P60764, P60763, Q05144, P15153, P48554, Q9TU25, Q6RUV5, P63001, P63000, P40792, Q03206|
|Predicted||Bovine, C.Elegans, Chicken, Drosophila, Monkey, Mouse, Pig, Rat, Yeast, Zebrafish|
|Calculated MW||22659 Da|
|Antigen Region||48-76 aa|
|Other Names||Rho-related GTP-binding protein RhoQ, Ras-like protein TC10, Ras-like protein family member 7A, RHOQ, ARHQ, RASL7A, TC10|
|Target/Specificity||This TC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the Central region of human TC10.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TC10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ARHQ, RASL7A, TC10|
|Function||Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.|
|Cellular Location||Cytoplasm. Cell membrane; Lipid-anchor|
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