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PAOX Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q6QHF9 |
| Other Accession | NP_997010.1, NP_997011.1, NP_690875.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 55513 Da |
| Antigen Region | 467-496 aa |
| Gene ID | 196743 |
|---|---|
| Other Names | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, Polyamine oxidase, PAOX, PAO |
| Target/Specificity | This PAOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-496 amino acids from the Central region of human PAOX. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PAOX Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PAOX |
|---|---|
| Synonyms | PAO |
| Function | Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)- acetylspermidine to putrescine. Substrate specificity: N(1)- acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380). |
| Cellular Location | Peroxisome. Cytoplasm |
| Tissue Location | Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 365.00
$ 140.00
Cat# AP5864c
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