ADSSL1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
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Primary Accession | Q8N142 |
Other Accession | A4Z6H0, P28650, A5PJR4, NP_689541.1, NP_954634.1 |
Reactivity | Human, Mouse |
Predicted | Bovine, Pig |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 50208 Da |
Antigen Region | 96-123 aa |
Gene ID | 122622 |
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Other Names | Adenylosuccinate synthetase isozyme 1 {ECO:0000255|HAMAP-Rule:MF_03126}, AMPSase 1 {ECO:0000255|HAMAP-Rule:MF_03126}, AdSS 1 {ECO:0000255|HAMAP-Rule:MF_03126}, 6344 {ECO:0000255|HAMAP-Rule:MF_03126}, Adenylosuccinate synthetase, basic isozyme {ECO:0000255|HAMAP-Rule:MF_03126}, Adenylosuccinate synthetase, muscle isozyme {ECO:0000255|HAMAP-Rule:MF_03126}, M-type adenylosuccinate synthetase {ECO:0000255|HAMAP-Rule:MF_03126}, IMP--aspartate ligase 1 {ECO:0000255|HAMAP-Rule:MF_03126}, ADSSL1 {ECO:0000255|HAMAP-Rule:MF_03126} |
Target/Specificity | This ADSSL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-123 amino acids from the N-terminal region of human ADSSL1. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ADSSL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADSS1 (HGNC:20093) |
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Function | Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. |
Cellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03126, ECO:0000269|PubMed:15786719} |
Tissue Location | Predominantly expressed in skeletal muscle and heart, as well as in several hematopoietic cell lines and solid tumors |
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