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SAMSN1 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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United States
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Ordering Information
Catalog # Size Availability Price  
AP5877c 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP5877c-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
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SAMSN1 Antibody (Center) - Product info

ApplicationWB, IHC, FC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ9NSI8
Other AccessionNP_071419.3
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW41708 Da

SAMSN1 Antibody (Center) - Additional info

Gene ID 64092
Other Names
SAMSN1; HACS1; SAM domain-containing protein SAMSN-1; Hematopoietic adaptor containing SH3 and SAM domains 1; Nash1; SAM domain, SH3 domain and nuclear localization signals protein 1; SH3-SAM adaptor protein
Target/Specificity
This SAMSN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-291 amino acids from the Central region of human SAMSN1.
Dilution
WB~~1:100~500
IHC~~1:50~100
FC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
SAMSN1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.

SAMSN1 Antibody (Center) - Protein Information

Name SAMSN1
Synonyms HACS1
Function
Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation (By similarity)
Cellular Location
Nucleus. Cytoplasm (By similarity). Cell projection, ruffle (By similarity). Note=Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles (By similarity)
Tissue Location
Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood

SAMSN1 Antibody (Center) - Related products

AP5877c: SAMSN1 Antibody (Center)

BP5877c: SAMSN1 Antibody (Center) Blocking peptide

AF1955a: SAMSN1 Antibody

SAMSN1 Antibody (Center) - Application data

  • SAMSN1 Antibody (Center) (Cat. #AP5877c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SAMSN1 antibody detected the SAMSN1 protein (arrow).

  • SAMSN1 Antibody (Center) (Cat. #AP5877c) immunohistochemistry analysis in formalin fixed and paraffin embedded human esophagus carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SAMSN1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

  • SAMSN1 Antibody (Center) (Cat. #AP5877c) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

SAMSN1 Antibody (Center) - Research Areas

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