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> home > Products > Primary Antibodies > Antibody Collections > Mitochondrion > COQ7 Antibody (C-term)
COQ7 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| IHC-P, FC, WB, E |
|---|---|
| Primary Accession | Q99807 |
| Other Accession | NP_057222.2, NP_001177912.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 24277 Da |
| Antigen Region | 162-191 aa |
| Gene ID | 10229 |
|---|---|
| Other Names | Ubiquinone biosynthesis protein COQ7 homolog, Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog, COQ7 |
| Target/Specificity | This COQ7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the C-terminal region of human COQ7. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | COQ7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | COQ7 {ECO:0000255|HAMAP-Rule:MF_03194} |
|---|---|
| Function | Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis (By similarity). Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides (By similarity). Involved in lifespan determination in a ubiquinone-independent manner (By similarity). Plays a role in modulating mitochondrial stress responses, acting in the nucleus, perhaps via regulating gene expression, independent of its characterized mitochondrial function in ubiquinone biosynthesis (PubMed:25961505). |
| Cellular Location | Mitochondrion inner membrane {ECO:0000255|HAMAP- Rule:MF_03194}; Peripheral membrane protein {ECO:0000255|HAMAP- Rule:MF_03194}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03194} Mitochondrion. Nucleus. Chromosome |
| Tissue Location | Expressed dominantly in heart and skeletal muscle. |
Research Areas
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$ 365.00
$ 140.00
Cat# AP5880b
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