|Application ||WB, IHC-P, FC, E|
|Other Accession||P11442, Q68FD5, P49951, NP_004850.1|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||191615 Da|
|Antigen Region||1019-1048 aa|
|Other Names||Clathrin heavy chain 1, Clathrin heavy chain on chromosome 17, CLH-17, CLTC, CLH17, CLTCL2, KIAA0034|
|Target/Specificity||This CLTC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1019-1048 amino acids from the Central region of human CLTC.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CLTC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CLH17, CLTCL2, KIAA0034|
|Function||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.|
|Cellular Location||Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Melanosome. Note=Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV|
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