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TMUB1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TMUB1 Antibody  (Center) AP5928c
    TMUB1 Antibody (Center) (Cat. #AP5928c) western blot analysis in mouse spleen tissue lysates (15ug/lane).This demonstrates the TMUB1 antibody detected TMUB1 protein (arrow).
  • IHC-P - TMUB1 Antibody  (Center) AP5928c
    TMUB1 antibody (Center) (Cat. #AP5928c) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TMUB1 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BVT8
Other Accession Q53AQ4, NP_001129516.1, NP_113622.1
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 26261 Da
Antigen Region 112-141 aa
Additional Information
Gene ID 83590
Other Names Transmembrane and ubiquitin-like domain-containing protein 1, Dendritic cell-derived ubiquitin-like protein, DULP, Hepatocyte odd protein shuttling protein, Ubiquitin-like protein SB144, TMUB1, C7orf21, DULP, HOPS
Target/Specificity This TMUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-141 amino acids from the Central region of human TMUB1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTMUB1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMUB1
Synonyms C7orf21, DULP, HOPS
Function Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR (PubMed:21343306). Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity). Acts as negative regulator of hepatocyte growth during regeneration (By similarity).
Cellular Location Membrane {ECO:0000250|UniProtKB:Q9JMG3}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9JMG3}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9JMG3}. Recycling endosome {ECO:0000250|UniProtKB:Q53AQ4}. Cytoplasm {ECO:0000250|UniProtKB:Q9JMG3}. Nucleus {ECO:0000250|UniProtKB:Q9JMG3}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9JMG3}
Tissue Location Ubiquitously expressed with highest levels in mammary and thyroid glands, bone marrow and spleen; limited expression in cardiac, pancreatic and ovarian tissues
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Cat# AP5928c
(40 western blots)
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