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USP49 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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United States
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Ordering Information
Catalog # SizeAvailability Available Date  
AP5947a 400 µl
(40 western blots)
Backorder 4 months
AP5947a-ev 80 µl
(8 western blots)
Backorder 4 months
  • Specification
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USP49 Antibody (N-term) - Product info

Application
  • Applications Legend:
  • WB=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary AccessionQ70CQ1
Other AccessionQ6P9L4, NP_061031.2
ReactivityHuman, Mouse
IsotypeRabbit Ig
Calculated MW79198 Da

USP49 Antibody (N-term) - Additional info

Gene ID 25862
Other Names
USP49; Ubiquitin carboxyl-terminal hydrolase 49; Deubiquitinating enzyme 49; Ubiquitin thioesterase 49; Ubiquitin-specific-processing protease 49
Target/Specificity
This USP49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human USP49.
Dilution
WB~~1:1000
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
USP49 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.

USP49 Antibody (N-term) - Protein Information

Name USP49
Function
Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.
Cellular Location
Nucleus (Probable).

USP49 Antibody (N-term) - Related products

BP5947a: USP49 Antibody (N-term) Blocking peptide

USP49 Antibody (N-term) - Research Areas

Application data

  • WB - USP49 Antibody (N-term) AP5947a

    USP49 Antibody (N-term) (Cat. #AP5947a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the USP49 antibody detected the USP49 protein (arrow).

  • WB - USP49 Antibody (N-term) AP5947a

    USP49 Antibody (N-term) (Cat. #AP5947a) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the USP49 antibody detected USP49 protein (arrow).

  • WB - USP49 Antibody (N-term) AP5947a
  • WB - USP49 Antibody (N-term) AP5947a

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