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USP49 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q70CQ1 |
| Other Accession | Q6P9L4, NP_061031.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 79198 Da |
| Antigen Region | 33-61 aa |
| Gene ID | 25862 |
|---|---|
| Other Names | Ubiquitin carboxyl-terminal hydrolase 49, Deubiquitinating enzyme 49, Ubiquitin thioesterase 49, Ubiquitin-specific-processing protease 49, USP49 |
| Target/Specificity | This USP49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human USP49. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | USP49 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | USP49 |
|---|---|
| Function | Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons. |
| Cellular Location | Nucleus. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# AP5947a
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