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USP49 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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United States
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Ordering Information
Catalog # SizeAvailability Available Date  
AP5947a 400 µl
(40 western blots)
Backorder 4 months
AP5947a-ev 80 µl
(8 western blots)
Backorder 4 months
  • Specification
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USP49 Antibody (N-term) - Product Information

Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary AccessionQ70CQ1
Other AccessionQ6P9L4, NP_061031.2
ReactivityHuman, Mouse
Immunity Source (Host) Rabbit
Isotype Rabbit Ig
Calculated MW 79198 Da
Antigen Region 33-61

USP49 Antibody (N-term) - Additional Information

Gene ID 25862
Other Names
USP49; Ubiquitin carboxyl-terminal hydrolase 49; Deubiquitinating enzyme 49; Ubiquitin thioesterase 49; Ubiquitin-specific-processing protease 49
Target/Specificity
This USP49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human USP49.
Dilution
WB~~1:1000
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
USP49 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.

USP49 Antibody (N-term) - Protein Information

Name USP49
Function
Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons. {ECO:0000269|PubMed:23824326}.
Cellular Location
Nucleus {ECO:0000305|PubMed:23824326}.

USP49 Antibody (N-term) - Related Products

BP5947a: USP49 Antibody (N-term) Blocking peptide

USP49 Antibody (N-term) - Research Areas

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