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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   USP49 Antibody (N-term)   

USP49 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - USP49 Antibody (N-term) AP5947a
    USP49 Antibody (N-term) (Cat. #AP5947a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the USP49 antibody detected the USP49 protein (arrow).
  • WB - USP49 Antibody (N-term) AP5947a
    USP49 Antibody (N-term) (Cat. #AP5947a) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the USP49 antibody detected USP49 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q70CQ1
Other Accession Q6P9L4, NP_061031.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 79198 Da
Antigen Region 33-61 aa
Additional Information
Gene ID 25862
Other Names Ubiquitin carboxyl-terminal hydrolase 49, Deubiquitinating enzyme 49, Ubiquitin thioesterase 49, Ubiquitin-specific-processing protease 49, USP49
Target/Specificity This USP49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human USP49.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Protein Information
Name USP49
Function Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.
Cellular Location Nucleus.
Research Areas
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Cat# AP5947a
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Quantity:
(40 western blots)
Availability: In Stock
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