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FKBP8 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FKBP8 Antibody (Center) AP5990c
    FKBP8 Antibody (Center) (Cat. #AP5990c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FKBP8 antibody detected the FKBP8 protein (arrow).
  • WB - FKBP8 Antibody (Center) AP5990c
    With HepG2 cell line lysate, the resolved proteins were electrophoretically transferred to PVDF membrane and incubated sequentially with primary antibody FKBP38 ( abgent, Cat. AP5990C, 1:1000, 4°C,overnight ) and horseradish peroxidase–conjugated second antibody. After washing, the bound antibody complex was detected using an ECL chemiluminescence reagentand XAR film (Kodak).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14318
Other Accession Q3B7U9, O35465, NP_036313.3
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44562 Da
Antigen Region 199-226 aa
Additional Information
Gene ID 23770
Other Names Peptidyl-prolyl cis-trans isomerase FKBP8, PPIase FKBP8, 38 kDa FK506-binding protein, 38 kDa FKBP, FKBP-38, hFKBP38, FK506-binding protein 8, FKBP-8, FKBPR38, Rotamase, FKBP8, FKBP38
Target/Specificity This FKBP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-226 amino acids from the Central region of human FKBP8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFKBP8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FKBP8
Synonyms FKBP38
Function Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Cellular Location Isoform 1: Mitochondrion membrane; Single- pass membrane protein; Cytoplasmic side
Tissue Location Widely expressed. Highest levels seen in the brain. Highly abundant in the retina
Research Areas
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$ 295.00
$ 99.00
Cat# AP5990c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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