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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ABCB7 Antibody (C-term)   

ABCB7 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ABCB7 Antibody (C-term) AP6114a
    The anti-ABCB7 C-term Pab (Cat. #AP6114a) is used in Western blot to detect ABCB7 in Jurkat cell lysate.
  • IHC-P - ABCB7 Antibody (C-term) AP6114a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75027
Other Accession Q704E8, Q61102, NP_004290
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 82641 Da
Antigen Region 718-746 aa
Additional Information
Gene ID 22
Other Names ATP-binding cassette sub-family B member 7, mitochondrial, ATP-binding cassette transporter 7, ABC transporter 7 protein, ABCB7, ABC7
Target/Specificity This ABCB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-746 amino acids from the C-terminal region of human ABCB7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsABCB7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABCB7
Synonyms ABC7
Function Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein {ECO:0000255|PROSITE- ProRule:PRU00441}
Research Areas
Citations (0)

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The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.


Allikmets, R., et al., Hum. Mol. Genet. 8(5):743-749 (1999).
Csere, P., et al., FEBS Lett. 441(2):266-270 (1998).
Mao, M., et al., Proc. Natl. Acad. Sci. U.S.A. 95(14):8175-8180 (1998).
Shimada, Y., et al., J. Hum. Genet. 43(2):115-122 (1998).
Savary, S., et al., Genomics 41(2):275-278 (1997).

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$ 295.00
$ 99.00
Cat# AP6114a
(40 western blots)
Availability: In Stock
Bulk Size
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