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ABCB8 Antibody (N-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP6129a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ABCB8 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | Q9NUT2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 79989 Da |
ABCB8 Antibody (N-term) - Additional info | |
| Gene ID 11194 | |
| Other Names ABCB8; MABC1; ATP-binding cassette sub-family B member 8, mitochondrial; Mitochondrial ATP-binding cassette 1 | |
| Target/Specificity This ABCB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29~59 amino acids from the N-terminal region of human ABCB8. | |
| Dilution WB~~1:50~100WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABCB8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABCB8 Antibody (N-term) - Protein Information | |
| Name ABCB8 | |
| Synonyms MABC1 | |
| Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein | |
| Tissue Location Ubiquitous. | |
ABCB8 Antibody (N-term) - Related products
AP6129a: ABCB8 Antibody (N-term)
RI10018: ABCB8 predesign siRNA
DC14901: Human ABCB8 cDNA Clone
ABCB8 Antibody (N-term) - Application data
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Western blot analysis of ABCB8 Antibody (N-term) (Cat.#AP6129a) in A2058 cell line lysates (35ug/lane). ABCB8 (arrow) was detected using the purified Pab.
ABCB8 Antibody (N-term) - Research Areas
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BACKGROUND
ABCB8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. The protein may also play a role in the transport of phospholipids into mitochondrial membranes.
REFERENCES
Saito S., Iida A., Sekine A.J. Hum. Genet. 47:38-50(2002)
