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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Jagged 2 (JAG2) Antibody (C-term)   

Jagged 2 (JAG2) Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Jagged 2 (JAG2) Antibody (C-term) AP6148A
    Western blot analysis of Jag2 (arrow) using JAG2 Antibody (C-term) (Cat.#AP6148a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the JAG2 gene (Lane 2) (Origene Technologies).
  • IHC-P - Jagged 2 (JAG2) Antibody (C-term) AP6148A
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y219
Other Accession NP_002217
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 133367 Da
Antigen Region 1209-1238 aa
Additional Information
Gene ID 3714
Other Names Protein jagged-2, Jagged2, hJ2, JAG2
Target/Specificity This Jagged 2 (JAG2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1209-1238 amino acids from the C-terminal region of human Jagged 2 (JAG2).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsJagged 2 (JAG2) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name JAG2
Function Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney
Research Areas
Citations (0)

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The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors.


Hayashi, T., et al., J. Androl. 22(6):999-1011 (2001).
Lindner, V., et al., Am. J. Pathol. 159(3):875-883 (2001).
Cereseto, A., et al., J. Cell. Physiol. 185(3):425-431 (2000).
Tsai, S., et al., Blood 96(3):950-957 (2000).
Deng, Y., et al., Genomics 63(1):133-138 (2000).

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Cat# AP6148A
(40 western blots)
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