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MMP7 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MMP7 Antibody (Center) AP6212a
    Anti-MMP7 Antibody (A132) at 1:1000 dilution + HL-60 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 30 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - MMP7 Antibody (Center) AP6212a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
  • IF - MMP7 Antibody (Center) AP6212a
    Confocal immunofluorescent analysis of MMP7 Antibody (Center) (Cat. #AP6212a) with 293 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09237
Other Accession NP_002414
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 29677 Da
Antigen Region 117-146 aa
Additional Information
Gene ID 4316
Other Names Matrilysin, Matrin, Matrix metalloproteinase-7, MMP-7, Pump-1 protease, Uterine metalloproteinase, MMP7, MPSL1, PUMP1
Target/Specificity This MMP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-146 amino acids from the Central region of human MMP7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMMP7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMP7
Synonyms MPSL1, PUMP1
Function Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
Cellular Location Secreted, extracellular space, extracellular matrix
Research Areas
Citations (0)

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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP7 degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.


Filippov, S., et al., J. Exp. Med. 198(6):925-935 (2003). Rivat, C., et al., FASEB J. 17(12):1721-1723 (2003). Fu, X., et al., J. Biol. Chem. 278(31):28403-28409 (2003). McGuire, J.K., et al., Am. J. Pathol. 162(6):1831-1843 (2003). Sumi, T., et al., Oncol. Rep. 10(2):345-349 (2003).

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$ 295.00
$ 99.00
Cat# AP6212a
(40 western blots)
Availability: In Stock
Bulk Size
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